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Could hand exercises sharpen the mind in Parkinson's?

NCT ID NCT07702929

Symptom relief Sponsor: Isfahan University of Medical Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This trial investigates whether sensory-motor hand rehabilitation can improve cognitive functions like memory, attention, and reaction time in people with Parkinson's disease. Thirty-two participants with mild cognitive impairment will be randomly assigned to either hand rehabilitation plus cognitive training or cognitive training alone. The study measures changes in thinking skills, hand function, and pain over one month after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hand sensorimotor rehabilitation
What this could lead to
If it works, this could point toward a simple hand exercise program that also boosts thinking skills in Parkinson's disease.
What could go wrong
This is a small, early-stage trial with only 32 participants, so results may not apply widely. The effect on cognition may be modest or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. A diagnosis of PD by a neurologist based on the Movement Disorders Society Clinical Diagnostic Criteria for Parkinson's Disease; 2. 45-65 years old: age of peak incidence of PD; 3. Minimum 2 years and maximum 10 years from initial diagnosis: stabilization of the disease process and medications; 4. disability level of at most 3 in the Modified Hoehn and Yahr Scale: physically independent; 5. Mild cognitive impairment: score between 20 and 26 in Montreal cognitive assessment; 6. Signing the written informed consent. Exclusion Criteria: 1. Patients with neurological diseases other than PD 2. Patients with orthopedic and internal diseases that would make participation in the study difficult

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Parkinson disease (disorder)

How to take part

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  1. The official record

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  2. A doctor treating you

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