Suction device vs gauze: race to heal open wounds
NCT ID NCT07832162
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers compare two ways to treat open contaminated wounds: vacuum-assisted closure (VAC) therapy and conventional saline-soaked dressings. Adults aged 15 to 60 with wounds 5 to 10 cm are randomly assigned to one method. The main question is which approach heals wounds faster, measured in days. The trial also tracks infections, hospital stay length, and whether further surgery is needed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vacuum-assisted closure (VAC) therapy, a device that applies suction to a sealed wound dressing
- What this could lead to
- If VAC heals wounds faster than standard dressings, hospitals could adopt it more widely for contaminated wounds and shorten patient stays.
- What could go wrong
- This is a small single-center study of 60 people with specific wound types, so its results may not apply to other wounds or settings. VAC also requires special equipment and trained staff.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Sep 2026
An estimate. Start dates often move.
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
15 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients having open contaminated and dirty wounds of size 5 - 10cm as per operational definition. * Patients between ages 15 to 60 years. * Both gender * ASA grade I \& II * Willing to provide written informed consent. Exclusion Criteria: * Patients with wounds having dry eschar, malignancy in wound, untreated osteomyelitis, exposed blood vessels and organs, long term anticoagulant therapy, bleeding disorders and fistula to organ / body cavities. Dermatological disorders like acute dermatitis, fungal infections of perianal region. * All the patients presented with exposed bone, tendons or nerve will be excluded from study * Pregnant women. * Patients on medications, such as corticosteroids, immunosuppressive agents or chemotherapy. All above will be assessed on history and documented medical history.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Wound healing are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Jinnah Postgraduate Medical Centre
Karachi, Sindh, 74600, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A dissolvable dressing that leaches steroid into healing sinuses
- Blood tests may reveal hidden healing power of bone marrow stem cells
- Can age slow down dental healing? a study investigates
- Can a seaweed extract help bones regrow in the jaw?
- Can a Blood-Based clot improve mouth healing in people with obesity?
- Seaweed gel may speed healing after dental implants — a trial puts it to the test