Monthly shot vs. daily pill: which works better for veterans with opioid addiction?

NCT ID NCT04375033

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 28 times

Summary

This study tests whether a once-monthly injection of buprenorphine helps veterans with opioid use disorder stay in treatment and avoid opioids better than the standard daily tablet. About 952 veterans will take part for up to a year. The goal is to find a more effective way to manage this chronic condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bay Pines VA Healthcare System, Pay Pines, FL

    RECRUITING

    Bay Pines, Florida, 33744-0000, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • CERC (VISN1, West Haven, CT)

    RECRUITING

    West Haven, Connecticut, 06516-2770, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clement J. Zablocki VA Medical Center, Milwaukee, WI

    RECRUITING

    Milwaukee, Wisconsin, 53295-0001, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Dayton VA Medical Center, Dayton, OH

    RECRUITING

    Dayton, Ohio, 45428, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hampton VA Medical Center, Hampton, VA

    RECRUITING

    Hampton, Virginia, 23667, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Huntington VA Medical Center, Huntington, WV

    NOT_YET_RECRUITING

    Huntington, West Virginia, 25704-9300, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Louis Stokes VA Medical Center, Cleveland, OH

    TERMINATED

    Cleveland, Ohio, 44106, United States

  • Minneapolis VA Health Care System, Minneapolis, MN

    TERMINATED

    Minneapolis, Minnesota, 55417-2309, United States

  • North Florida/South Georgia Veterans Health System, Gainesville, FL

    RECRUITING

    Gainesville, Florida, 32608-1135, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Philadelphia MultiService Center, Philadelphia, PA

    RECRUITING

    Philadelphia, Pennsylvania, 19106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Phoenix VA Health Care System, Phoenix, AZ

    RECRUITING

    Phoenix, Arizona, 85012, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Providence VA Medical Center, Providence, RI

    TERMINATED

    Providence, Rhode Island, 02908-4734, United States

  • Salem VA Medical Center, Salem, VA

    RECRUITING

    Salem, Virginia, 24153-6404, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • San Francisco VA Medical Center, San Francisco, CA

    RECRUITING

    San Francisco, California, 94121-1563, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Tuscaloosa VA Medical Center, Tuscaloosa, AL

    TERMINATED

    Tuscaloosa, Alabama, 35404-5015, United States

  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

    TERMINATED

    Boston, Massachusetts, 02130, United States

  • VA Connecticut Healthcare System West Haven Campus, West Haven, CT

    ACTIVE_NOT_RECRUITING

    West Haven, Connecticut, 06516-2770, United States

  • VA Long Beach Healthcare System, Long Beach, CA

    RECRUITING

    Long Beach, California, 90822, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX

    RECRUITING

    Dallas, Texas, 75216-7167, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Palo Alto Health Care System, Palo Alto, CA

    RECRUITING

    Palo Alto, California, 94304-1207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

    TERMINATED

    Pittsburgh, Pennsylvania, 15240, United States

  • VA Puget Sound Health Care System Seattle Division, Seattle, WA

    RECRUITING

    Seattle, Washington, 98108-1532, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Salt Lake City Health Care System, Salt Lake City, UT

    RECRUITING

    Salt Lake City, Utah, 84148-0001, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • White River Junction VA Medical Center, White River Junction, VT

    TERMINATED

    White River Junction, Vermont, 05001-3833, United States

  • Wilmington VA Medical Center, Wilmington, DE

    RECRUITING

    Wilmington, Delaware, 19805-4917, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.