New hope for Crohn's: ustekinumab trial targets chinese patients

NCT ID NCT05029921

Completed Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested the drug ustekinumab (STELARA) in 182 Chinese adults with moderate-to-severe Crohn's disease. The goal was to see if the drug could reduce symptoms and heal the gut lining over 52 weeks. Participants received the drug by IV and later by injection, and researchers tracked remission and endoscopic improvement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ustekinumab (STELARA)

What this could lead to

If successful, this could confirm that ustekinumab is a safe and effective treatment option for Chinese patients with moderate-to-severe Crohn's disease.

What could go wrong

This is a single-arm, open-label study with no placebo group, so results may be less reliable. Side effects like infections or allergic reactions are possible, and long-term benefits are not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE

Contacts and locations

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Locations

Affiliated Hospital of Zunyi Medical University

Zunyi, 563000, China
Anhui Province Hospital

Hefei, 230001, China
Changzhou No 2 Peoples Hospital

Changzhou, 213000, China
Guangzhou First Municipal People's Hospital

Guangzhou, 510180, China
Huashan Hospital Fudan University

Shanghai, 200040, China
Huzhou central hospital

Huzhou, 313099, China
Jiangsu Province Hospital

Nanjing, 210029, China
Jinhua municipal central hospital

Jinhua, 321000, China
Ningbo medical center lihuili hospital

Ningbo, 315000, China
Peking University Shenzhen Hospital

Shenzhen, 518036, China
Peking University Third Hospital

Beijing, 100191, China
Renmin Hospital of Wuhan University

Wuhan, 430060, China
Shanghai 10th Peoples Hospital

Shanghai, 200072, China
Shanghai East Hospital

Shanghai, 200120, China
Shengjing Hospital Of China Medical University

Shenyang, 110004, China
Sir Run Run Shaw Hospital Zhejiang University School of Medicine

Hangzhou, 310016, China
The First Affiliated Hospital Sun Yat sen University

Guangzhou, 510080, China
The First Affiliated Hospital of Fujian Medical University

Fuzhou, 350005, China
The First Affiliated Hospital of NanChang University

Nanchang, 330006, China
The Military General Hospital of Beijing PLA

Beijing, 100700, China
The Second Affiliated Hospital of Zhejiang University

Hangzhou, 310003, China
The Second Hospital Affiliated To Suzhou University

Suzhou, 215168, China
The Sixth Affiliated Hospital of Sun Yat-sen University

Guangzhou, China
The second Xiangya Hospital of Central South University

Changsha, 200120, China
Tongji Hospital, Tongji Medical College of HUST

Wuhan, 430030, China
West China Hospital Sichuan University

Chengdu, 610041, China
Wuxi People s Hospital

Wuxi, 214023, China
Yangzhou First People's Hospital

Yangzhou, 225001, China
Zhongda Hospital Southeast University

Nanjing, 210000, China