Can an Immune-Calming drug tame Behçet's Flare-Ups?

NCT ID NCT02648581

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This small study tested ustekinumab, a drug that calms the immune system, in 16 adults with Behçet disease. The goal was to see if it could reduce mouth ulcers and eye inflammation. The trial is complete, but because it's early and small, we don't yet know if the drug will become a standard treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ustekinumab (a drug that calms the immune system)

What this could lead to

If it works, this could point toward a new treatment option for Behçet disease, reducing painful ulcers and eye inflammation.

What could go wrong

This is a very small, early-phase trial with only 16 people, so results may not apply to everyone. The drug may not work or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Behcet disease ulcer disease uveitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Cochin, Department of Internal Medicine, National Reference Center for Autoimmune and Systemic Diseases

    Paris, Paris, 75014, France