Can a quick skin scan reveal hidden inflammation in arthritis?

NCT ID NCT07329556

Not yet recruiting Knowledge-focused Sponsor: Bursa City Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will measure harmful molecules called AGEs in 300 people with various rheumatic diseases (like rheumatoid arthritis and ankylosing spondylitis) and compare them to healthy volunteers. AGEs build up over time and can cause inflammation. Researchers will use a non-invasive device that shines a light on the skin to measure AGE levels. The goal is to better understand how AGEs relate to rheumatic diseases and whether this simple test could be used as a biomarker in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple, non-invasive skin test to help monitor or predict disease activity in rheumatic conditions.
What could go wrong: This is an observational study, not a treatment trial. It only measures AGE levels and does not test any therapy, so it cannot directly improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ankylosing spondylitis Behcet disease connective tissue disorder Crystal Arthropathies crystal arthropathy familial Mediterranean fever psoriatic arthritis reactive arthritis rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANKYLOSING SPONDYLITIS CONNECTIVE TISSUE DISEASES CRYSTAL ARTHROPATHIES FAMILIAL MEDITERRANEAN FEVER (FMF) PSORIATIC ARTHRITIS REACTIVE ARTHRITIS (REA) RHEUMATOID ARTHRITIS (RA)

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