Crohn's patients who lost drug response may benefit from higher doses

NCT ID NCT04245215

First seen Apr 16, 2026 · Last updated May 02, 2026 · Updated 4 times

Summary

This study looked at 108 adults with Crohn's disease whose symptoms returned while on the standard dose of ustekinumab. Researchers tested whether giving a stronger re-induction dose followed by either the usual or more frequent maintenance shots could bring back control. The goal was to see if patients could achieve remission without steroids and with lower inflammation markers.

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Contacts and locations

Locations

  • Ingrid Arijs

    Zaventem, 1930, Belgium

Conditions

Explore the condition pages connected to this study.