Dissolving stent could spare kidney stone patients a second procedure
NCT ID NCT04565795
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is testing a new type of ureteral stent that is designed to slowly dissolve and pass out of the body on its own after being placed during kidney stone surgery. The goal is to see if it safely drains urine and breaks down within 90 days, so patients don't need a second procedure to remove it. About 87 adults who had a straightforward stone removal will be followed for three months to check for complications and how well the stent works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Uriprene® Degradable Temporary Ureteral Stent
- What this could lead to
- If it works, this could offer a safer, more convenient option for patients needing a temporary stent after kidney stone surgery, eliminating the need for a second procedure to remove it.
- What could go wrong
- This is an early-stage, non-randomized trial with only 87 participants, so results may not apply to everyone. The stent might not degrade as expected or could cause side effects like pain or infection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mayo Clinic Arizona
RECRUITINGPhoenix, Arizona, 85054, United States
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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University of California Los Angeles
RECRUITINGLos Angeles, California, 90404, United States
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University of Florida
RECRUITINGGainesville, Florida, 32610, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a simple tool predict who will be Stone-Free after kidney surgery?
- Which kidney stone technique leaves no stone behind?
- Which surgery is safer for a single kidney with stones? a Head-to-Head trial
- New combo therapy may simplify kidney stone removal
- Kidney stone patients may skip stent after surgery, study hints
- New hope for kidney stone patients: safer pain relief after surgery?