Adaptive radiation aims to outsmart aggressive brain tumors
NCT ID NCT05720078
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study tests whether a personalized, two-phase radiation therapy approach can better control glioblastoma, an aggressive brain cancer. The treatment adapts the radiation plan based on tumor changes during therapy, potentially targeting the tumor more precisely while sparing healthy tissue. Researchers will compare local control, survival, and side effects between this adaptive method and standard radiation in 70 adults with newly diagnosed glioblastoma.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
adaptive radiation therapy
What this could lead to
If successful, this approach could improve local tumor control and reduce side effects for people with glioblastoma.
What could go wrong
This is a relatively small, early-phase study, so results may not apply broadly. The adaptive technique is complex and may not improve outcomes over standard care.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N3M5, Canada