MS mystery: what happens inside the brain?

NCT ID NCT02659956

Recruiting now Knowledge-focused Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 35 times

Summary

This study aims to understand how multiple sclerosis (MS) damages the brain and spinal cord over a person's lifetime. Researchers will follow 250 adults with MS or similar conditions, using yearly MRI scans, eye tests, and other exams. Participants agree to donate their brain and spinal cord for autopsy after death, so scientists can compare living images with actual tissue changes. The goal is to better understand MS progression, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

MULTIPLE SCLEROSIS