Why some ICU patients Can't leave the ventilator: diaphragm weakness under the microscope

NCT ID NCT03140267

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study followed 22 ICU patients who had trouble being taken off a breathing machine (ventilator). Researchers measured two key aspects of the diaphragm—strength and endurance—over 18 hours to see which one is more lacking. The goal was to understand the root cause of weaning failure so that future breathing muscle training can be more effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help design better breathing muscle training programs for ICU patients struggling to come off ventilators.

What could go wrong

This is a very small, observational study (22 people) that only measures muscle function—it does not test any treatment, so it may not lead to direct improvements.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Haut-Lévêque

    Bordeaux, 33000, France

  • Hôpital Pellegrin

    Bordeaux, 33000, France