Ablation without X-Rays: a new way to fix irregular heartbeats?

NCT ID NCT07762742

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial tests whether a heart procedure called pulsed field ablation can be guided using only ultrasound, avoiding the use of X-rays (fluoroscopy), in people with paroxysmal atrial fibrillation. The study compares the success of completely isolating the pulmonary veins—a key step in the procedure—between ultrasound-only and standard fluoroscopy guidance. If ultrasound works just as well, it could reduce radiation exposure for patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Percutaneous pulsed field ablation (PFA) procedure
What this could lead to
If ultrasound-only guidance works as well as fluoroscopy, it could make PFA safer by eliminating radiation exposure during the procedure.
What could go wrong
This is an early-stage comparison, and ultrasound guidance may not be as effective or safe in all patients. The trial is non-inferiority, so it only aims to show it's not worse, not better.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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