New ultra-low dose CT could slash radiation for HHT lung checks

NCT ID NCT04108052

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether an ultra-low dose chest CT scan can find lung blood vessel malformations in people with hereditary hemorrhagic telangiectasia (HHT) as well as the standard low-dose CT scan, but with much less radiation. 45 HHT patients received both scans, and radiologists compared the results. The goal is to reduce the radiation exposure from repeated lifetime scans without missing dangerous malformations that can cause strokes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ultra-low dose CT scan (radiation)

What this could lead to

If successful, this could allow HHT patients to get safer, lower-radiation lung scans for routine monitoring.

What could go wrong

This is a small, completed study with only 45 participants. The ultra-low dose images may be too noisy to reliably detect small malformations, limiting its use in practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

arteriovenous hemangioma/malformation disease hereditary hemorrhagic telangiectasia Pulmonary Arteriovenous Fistulas

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospices Civils de Lyon - Hopital Louis Pradel

    Bron, 69500, France