New ultra-low dose CT could slash radiation for HHT lung checks

NCT ID NCT04108052

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study tested whether an ultra-low dose chest CT scan can find lung blood vessel malformations in people with hereditary hemorrhagic telangiectasia (HHT) as well as the standard low-dose CT scan, but with much less radiation. 45 HHT patients received both scans, and radiologists compared the results. The goal is to reduce the radiation exposure from repeated lifetime scans without missing dangerous malformations that can cause strokes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
ultra-low dose CT scan (radiation)
What this could lead to
If successful, this could allow HHT patients to get safer, lower-radiation lung scans for routine monitoring.
What could go wrong
This is a small, completed study with only 45 participants. The ultra-low dose images may be too noisy to reliably detect small malformations, limiting its use in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospices Civils de Lyon - Hopital Louis Pradel

    Bron, 69500, France

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