New hope for HHT nosebleeds: drug trial aims to stop the bleeding
NCT ID NCT04976036
First seen Mar 26, 2026 · Last updated May 16, 2026 · Updated 8 times
Summary
This study tests whether a twice-daily capsule called nintedanib can reduce the frequency and severity of nosebleeds in people with hereditary hemorrhagic telangiectasia (HHT), a condition that causes abnormal blood vessels. About 48 adults with moderate to severe nosebleeds will be randomly assigned to receive nintedanib or a placebo for 16 weeks. Participants will track their nosebleeds daily in a diary for 8 months, including a 2-month observation period before treatment and 8 weeks after treatment ends.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Angiology Department, Lausanne University Hospital
COMPLETEDLausanne, Canton of Vaud, 1011, Switzerland
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Clermont-Ferrand university hospital
RECRUITINGClermont-Ferrand, 63000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Lyon University Hospital, Dpt of genetics
RECRUITINGBron, 69677, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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