Exercise echo may catch silent heart failure in rare HHT liver disease

NCT ID NCT05954481

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed pilot study looked at 47 adults with hereditary hemorrhagic telangiectasia (HHT) who also have liver involvement. Researchers used exercise echocardiography (heart ultrasound while pedaling) to measure lung artery pressure during exercise. The goal was to see if this test could detect early signs of heart failure before they show up at rest, potentially helping doctors decide when to consider advanced treatments like liver transplantation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

stress echocardiography

What this could lead to

If successful, this could lead to earlier detection of heart failure in HHT patients, potentially improving timing for treatments like liver transplantation.

What could go wrong

This is a small pilot study with only 47 participants, so results may not apply to all patients. It is observational and does not test a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hereditary hemorrhagic telangiectasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service Explorations fonctionnelles cardiovasculaires - Hôpital Louis Pradel

    Bron, 69677, France

  • Service génétique - Hôpital Femme Mère Enfant

    Bron, 69677, France