Shorter, stronger radiation for prostate cancer: a new hope?
NCT ID NCT04147806
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests two ultra-high-dose radiation schedules in 31 men with intermediate-risk prostate cancer. One group gets five high-dose sessions over a week; the other gets a single massive dose. The goal is to see if these shorter treatments are safe and can control the cancer. Participants are followed for at least 5 years to monitor side effects and tumor response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Radiation therapy (IGRT) with dexamethasone and tamsulosin
What this could lead to
If successful, this could lead to a shorter, more convenient radiation treatment for prostate cancer with fewer side effects.
What could go wrong
This is a very early Phase 1 pilot study with only 31 participants. The high radiation dose may cause unexpected urinary, rectal, or sexual side effects. Results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467-2490, United States