New drug targets rare BRAF mutations in advanced cancers

NCT ID NCT06400225

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 28 times

Summary

This study tests a drug called ulixertinib in 35 adults with advanced cancers that have certain BRAF gene changes (fusions or non-V600 mutations). The drug blocks signals that tell cancer cells to grow. The main goal is to see how many patients' tumors shrink or disappear. This is a phase 2 trial for people whose cancer has not responded to other treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.