Could stem cell secretome beat standard care for knee arthritis?

NCT ID NCT07337863

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a substance made from stem cells (called secretome) can reduce pain and improve knee function in people with moderate knee osteoarthritis. Fifty adults aged 40-70 will receive either the secretome or a standard treatment (sodium hyaluronate) via injection into the knee. The goal is to see if the secretome works better for easing symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

umbilical cord-derived mesenchymal stem cell secretome

What this could lead to

If it works, this could offer a new way to ease knee pain and improve function in people with moderate knee osteoarthritis.

What could go wrong

This is an early-to-mid-stage trial with only 50 participants, so results may not apply to everyone. The secretome is experimental and its long-term safety and effectiveness are not yet known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • RSUP Dr. Mohammad Hoesin Palembang

    Palembang, South Sumatera, Indonesia

    Contact Phone: •••-•••-•••• Email: •••••@•••••