New pill could stop Period-Linked migraines before they start

NCT ID NCT06417775

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests whether the drug ubrogepant can prevent menstrual migraines when taken daily for a week around each period. About 496 women with regular cycles and a history of menstrual migraines will receive either ubrogepant or a placebo for three cycles, then all may receive the drug for a year. The goal is to see if it safely reduces the number of migraine days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ubrogepant (UBRELVY)

What this could lead to

If successful, this could offer a new short-term preventive option for women with menstrual migraines, reducing the number of migraine days each cycle.

What could go wrong

This is a phase 3 trial, but it's still testing an investigational use. The drug may not work better than placebo, and side effects are possible. Results may not apply to all migraine types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MIGRAINE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Abington Neurological Associates - Abington /ID# 257164
RECRUITING

Abington, Pennsylvania, 19001, United States
Accel Research Sites - Lakeland Clinical Research Unit /ID# 257874
RECRUITING

Lakeland, Florida, 33803, United States

Contact Phone: •••-•••-••••
Accel Research Sites Network - DeLand Clinical Research Unit /ID# 257403
RECRUITING

DeLand, Florida, 32720, United States

Contact Phone: •••-•••-••••
Accellacare - McFarland Clinic /ID# 257834
RECRUITING

Ames, Iowa, 50010, United States

Contact Phone: •••-•••-••••
Accellacare - South Hawthorne Road - Winston-Salem /ID# 257731
RECRUITING

Winston-Salem, North Carolina, 27103, United States
Accellacare - South Hawthorne Road - Winston-Salem /ID# 257850
RECRUITING

Winston-Salem, North Carolina, 27103, United States
Advanced Research Institute /ID# 257853
RECRUITING

Ogden, Utah, 84405, United States
Albuquerque Clinical Trials, Inc. /ID# 257212
RECRUITING

Albuquerque, New Mexico, 87102, United States
Alliance For Multispeciality Research - Wichita East /ID# 257148
RECRUITING

Wichita, Kansas, 67207, United States
Alliance for Multispecialty Research - Clinical Research Associates /ID# 257851
RECRUITING

Norfolk, Virginia, 23502, United States

Contact Phone: •••-•••-••••
Alliance for Multispecialty Research - Knoxville /ID# 257846
RECRUITING

Knoxville, Tennessee, 37920, United States
Alliance for Multispecialty Research LLC /ID# 257839
RECRUITING

Newton, Kansas, 67114, United States
Artemis Institute for Clinical Research - San Diego /ID# 257134
RECRUITING

San Diego, California, 92103-2204, United States
Axiom Research - Irvine /ID# 264083
RECRUITING

Irvine, California, 92604, United States
Axiom Research /ID# 257833
RECRUITING

Colton, California, 92324, United States

Contact Phone: •••-•••-••••
Axiom Research, LLC-Los Angeles /ID# 264085
RECRUITING

Glendale, California, 91206, United States
BDH Research /ID# 262851
RECRUITING

San Juan, 00927, Puerto Rico
BNL Health - Los Angeles Headache Center /ID# 257237
RECRUITING

Los Angeles, California, 90067-2001, United States

Contact Phone: •••-•••-••••
BTC of New Bedford /ID# 257128
COMPLETED

New Bedford, Massachusetts, 02740, United States
Bio Behavioral Health, Inc /ID# 257140
RECRUITING

Toms River, New Jersey, 08755-6434, United States
Boston Clinical Trials /ID# 257132
RECRUITING

Boston, Massachusetts, 02131-2515, United States

Contact Phone: •••-•••-••••
C7 Research /ID# 272815
RECRUITING

Cleveland, Ohio, 44109, United States

Contact Phone: •••-•••-••••
CTI Clinical Research Center /ID# 257162
RECRUITING

Cincinnati, Ohio, 45212-3784, United States
CenExel Collaborative Neuroscience Research /ID# 257828
COMPLETED

Los Alamitos, California, 90720, United States
Central Research Associates /ID# 260161
COMPLETED

Birmingham, Alabama, 35205, United States
Central States Research /ID# 277867
RECRUITING

Tulsa, Oklahoma, 74136, United States
Centricity Research Columbus /ID# 257221
RECRUITING

Columbus, Ohio, 43213, United States
Charlottesville Medical Research /ID# 257154
RECRUITING

Charlottesville, Virginia, 22911, United States
Clinical Neuroscience Solutions, Inc /ID# 257190
COMPLETED

Orlando, Florida, 32801-2986, United States
Clinical Research Atlanta - Headlands LLC /ID# 260181
RECRUITING

Stockbridge, Georgia, 30281-9054, United States
Clinical Research of Philadelphia, LLC /ID# 257197
RECRUITING

Philadelphia, Pennsylvania, 19114, United States
Clinpoint Trials /ID# 274524
ACTIVE_NOT_RECRUITING

Waxahachie, Texas, 75165, United States
Clinvest Research LLC /ID# 257215
RECRUITING

Springfield, Missouri, 65807, United States
Coastal Carolina Research Center - North Charleston /ID# 257227
RECRUITING

North Charleston, South Carolina, 29405, United States
Cognitive Clinical Trials (CCT) - Papillion /ID# 260174
RECRUITING

Papillion, Nebraska, 68046-4131, United States
Collective Medical Research /ID# 257131
RECRUITING

Overland Park, Kansas, 66210, United States

Contact Phone: •••-•••-••••
Conquest Research /ID# 258314
RECRUITING

Winter Park, Florida, 32789, United States
Deaconess Midtown Hospital /ID# 257400
RECRUITING

Evansville, Indiana, 47710, United States
Dent Neurologic Institute - Amherst /ID# 257219
RECRUITING

Amherst, New York, 14226, United States
Elevate Clinical - Seabrook /ID# 274679
RECRUITING

Houston, Texas, 77058, United States
Epic Clinical Research - Lewisville /ID# 274480
RECRUITING

Lewisville, Texas, 75057, United States
Fieve Clinical Research, Inc. /ID# 257177
RECRUITING

New York, New York, 10017-1921, United States
Foothill Family Draper Clinic /ID# 277876
RECRUITING

Draper, Utah, 84020, United States
Foothills Research Center/CCT Research /ID# 260180
RECRUITING

Phoenix, Arizona, 85044, United States
FutureSearch Trials of Dallas, LP /ID# 257142
RECRUITING

Dallas, Texas, 75231, United States
FutureSearch Trials of Neurology /ID# 257186
RECRUITING

Austin, Texas, 78731, United States
Gilbert Neurology /ID# 260179
RECRUITING

Gilbert, Arizona, 85297, United States
Hawaii Pacific Neuroscience /ID# 274469
COMPLETED

Honolulu, Hawaii, 96817, United States
Headache Wellness Center /ID# 257136
RECRUITING

Greensboro, North Carolina, 27405, United States
Headlands PharmaSite /ID# 257208
RECRUITING

Baltimore, Maryland, 21208, United States
HealthCare Research Network - Hazelwood /ID# 257402
RECRUITING

Hazelwood, Missouri, 63042, United States

Contact Phone: •••-•••-••••
Healthcare Research Network /ID# 257868
RECRUITING

Tinley Park, Illinois, 60477, United States

Contact Phone: •••-•••-••••
Highland Clinical Research /ID# 257137
RECRUITING

Salt Lake City, Utah, 84124, United States
Hope Clinical Research /ID# 257867
RECRUITING

Canoga Park, California, 91303, United States
Houston Clinical Research Associates /ID# 272077
RECRUITING

Houston, Texas, 77090, United States

Contact Phone: •••-•••-••••
IMA Clinical Research Las Vegas /ID# 258679
COMPLETED

Las Vegas, Nevada, 89102-1955, United States
IMA Clinical Research Monroe - Wood /ID# 259362
COMPLETED

Monroe, Louisiana, 71201, United States
IMA Clinical Research Warren /ID# 263641
RECRUITING

Warren Township, New Jersey, 07059, United States
IMA Clinical Research Westchester /ID# 259157
RECRUITING

Hartsdale, New York, 10530, United States
ISIS Clinical Research Center /ID# 262858
RECRUITING

Guaynabo, 00969-2806, Puerto Rico
Indago Research and Health Center /ID# 277943
RECRUITING

Miami Lakes, Florida, 33016, United States

Contact Phone: •••-•••-••••
Instituto De Neurologia Dra. Ivonne Fraga, Psc /ID# 262852
RECRUITING

San Juan, 00918, Puerto Rico
J. Lewis Research - Salt Lake City - Foothill Drive /ID# 277877
COMPLETED

Salt Lake City, Utah, 84109, United States
J. Lewis Research, Inc. / Foothill Family Clinic South /ID# 258305
RECRUITING

Salt Lake City, Utah, 84121-6923, United States
KCA Neurology /ID# 274495
RECRUITING

Franklin, Tennessee, 37067, United States
Lillestol Research, LLC /ID# 257896
COMPLETED

Fargo, North Dakota, 58104, United States
Lynn Institute of Oklahoma City /ID# 257857
RECRUITING

Oklahoma City, Oklahoma, 73112, United States

Contact Phone: •••-•••-••••
M3 Wake Research - Convoy /ID# 257897
RECRUITING

San Diego, California, 92111, United States
M3 Wake Research - Newport Beach /ID# 257158
RECRUITING

Newport Beach, California, 92660, United States
M3 Wake Research-Las Vegas Rainbow /ID# 257895
RECRUITING

Las Vegas, Nevada, 89118-2557, United States
MD First Research - Chandler /ID# 262564
RECRUITING

Chandler, Arizona, 85286, United States
MedVadis Research /ID# 257156
RECRUITING

Waltham, Massachusetts, 02451, United States
Memorial Healthcare Institute For Neuroscience /ID# 274663
COMPLETED

Owosso, Michigan, 48867, United States
Methodist Physicians Clinic/CCT Research /ID# 260167
COMPLETED

Fremont, Nebraska, 68025, United States
Michigan Headache & Neurological Institute (MHNI) /ID# 257179
RECRUITING

Ann Arbor, Michigan, 48104-5131, United States
Mind+ Neurology /ID# 274486
RECRUITING

Mequon, Wisconsin, 53092, United States
Neuro Pain Research Center /ID# 257155
RECRUITING

Fresno, California, 93710, United States
NeuroTrials Research /ID# 274507
RECRUITING

Atlanta, Georgia, 30328, United States
Neurology Offices of South Florida, PLLC /ID# 257161
RECRUITING

Boca Raton, Florida, 33428-2231, United States

Contact Phone: •••-•••-••••
New England Institute for Clinical Research /ID# 264019
RECRUITING

Stamford, Connecticut, 06905, United States
Northwest Clinical Research Center /ID# 257381
RECRUITING

Bellevue, Washington, 98007, United States
Optimus Medical /ID# 257856
RECRUITING

San Francisco, California, 94102, United States
Partners In Clinical Research /ID# 257855
RECRUITING

Cumberland, Rhode Island, 02864, United States
Preferred Research Partners /ID# 262786
RECRUITING

Little Rock, Arkansas, 72211, United States
Preferred Research Partners /ID# 273128
COMPLETED

Little Rock, Arkansas, 72211, United States
Premier Neurology /ID# 260359
RECRUITING

Greenville, South Carolina, 29605, United States

Contact Phone: •••-•••-••••
Proven Endpoints LLC /ID# 273796
RECRUITING

Ridgeland, Mississippi, 39157, United States
Puget Sound Neurology /ID# 257174
RECRUITING

Tacoma, Washington, 25328, United States
Radiance Clinical Research /ID# 271727
RECRUITING

Lampasas, Texas, 76550, United States
Red Star Research, LLC /ID# 257871
RECRUITING

Lake Jackson, Texas, 77566, United States
Rehabilitation and Neurological Services /ID# 275593
RECRUITING

Huntsville, Alabama, 35805, United States
Rochester Clinical Research /ID# 257193
RECRUITING

New York, New York, 14609, United States

Contact Phone: •••-•••-••••
Sensible Healthcare /ID# 257198
RECRUITING

Ocoee, Florida, 34761, United States
Sms Clinical Research /ID# 278443
RECRUITING

Mesquite, Texas, 75149, United States
Summit Research Network - Portland - Northwest Vaughn Street /ID# 257139
RECRUITING

Portland, Oregon, 97210, United States
Sun Valley Research Center /ID# 257152
RECRUITING

Imperial, California, 92251-9401, United States
Tandem Clinical Research - Marrero - Barataria Boulevard /ID# 260146
COMPLETED

Marrero, Louisiana, 70072, United States
Trialmed-Synexus Clinical Research US, Inc. - Tucson /ID# 258309
COMPLETED

Tucson, Arizona, 85741, United States
True North Neurology /ID# 274672
RECRUITING

Port Jefferson Station, New York, 11776, United States
Upstate Clinical Research Associates /ID# 257163
RECRUITING

Williamsville, New York, 14221-6046, United States
Vaught Neurological Services /ID# 267519
RECRUITING

Beckley, West Virginia, 25801, United States
Velocity Clinical Research - Boise /ID# 257135
RECRUITING

Meridian, Idaho, 83642, United States
WR-ClinSearch /ID# 257160
RECRUITING

Chattanooga, Tennessee, 37421-1605, United States
Well Pharma Medical Research /ID# 257199
RECRUITING

Miami, Florida, 33143, United States
West Virginia Univ School Med /ID# 258898
RECRUITING

Morgantown, West Virginia, 26506, United States
Wright State Physicians Health Center /ID# 274708
RECRUITING

Fairborn, Ohio, 45324, United States