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Fewer dialysis sessions: can Twice-Weekly work as well?

NCT ID NCT07821788

Knowledge-focused Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 18, 2026 · Updated 2 times

Summary

Researchers at Assiut University Hospitals compare adults with kidney failure who receive hemodialysis twice a week versus three times a week. The study tracks health-related quality of life, dialysis adequacy, urine output, and hospitalizations over time. About 130 participants already on one of these schedules take part. The goal is to see whether less frequent dialysis can maintain good outcomes and improve daily life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If twice-weekly dialysis proves comparable, it could reduce treatment burden and travel time for some patients with kidney failure. It might also guide doctors in tailoring dialysis schedules to individual needs.
What could go wrong
This observational study cannot prove cause and effect, and results may not apply to all dialysis patients. Patients on twice-weekly schedules might have worse outcomes if their kidney function declines.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 130 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Feb 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults with end-stage kidney disease receiving maintenance in-center hemodialysis at Assiut University Hospitals.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- Age 18 years or older * Established end-stage kidney disease requiring maintenance hemodialysis * Receiving in-center maintenance hemodialysis at Assiut University Hospitals * On maintenance hemodialysis for at least one month before enrollment * Established twice-weekly or thrice-weekly schedule prescribed by the treating team * Clinically stable at recruitment * Able to understand and respond to the questionnaire * Written informed consent Exclusion Criteria: * \- Acute kidney injury without established end-stage kidney disease * Hemodialysis for less than one month * Peritoneal dialysis or kidney transplantation during follow-up * Acute severe illness requiring intensive care at recruitment * Severe cognitive, psychiatric or neurological impairment preventing reliable questionnaire responses * Active malignancy with expected survival too short to complete follow-up * Temporary dialysis solely for an acute indication * Refusal to participate * Permanent transfer to another dialysis center during follow-up

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kidney failure, chronic Quality of life

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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