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Can pedaling through dialysis make patients stronger?

NCT ID NCT07820514

Symptom relief Sponsor: Ricerca Nefrocenter Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Researchers are testing whether two kinds of exercise done during hemodialysis are safe and helpful for adults with kidney failure. Participants are assigned to cycle on a stationary bike, use elastic bands for resistance training, or receive standard dialysis care. The study measures blood pressure and heart rate during sessions, plus physical function, body composition, and quality of life over six months. The goal is to learn which exercise approach, if any, is well tolerated and improves health for people on long-term dialysis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
supervised aerobic and resistance exercise during hemodialysis
What this could lead to
If it works, exercise during dialysis could become a standard part of kidney failure care, helping people stay stronger and feel better while on long-term treatment.
What could go wrong
Exercise during dialysis can cause drops in blood pressure, dizziness, or cramps, and some participants may not tolerate it. The trial may also show no clear benefit over standard care, and results in a supervised research setting may not carry over to routine clinics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 312 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years. * Receiving maintenance hemodialysis for more than 3 months. * Clinically stable condition. * Ability and willingness to provide written informed consent. Exclusion Criteria: * Unstable angina. * Uncontrolled hypertension. * Any medical condition judged by the treating nephrologist to contraindicate or make intradialytic exercise unsafe

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney disease on hemodialysis Physical exercise behavior (liking/aversion)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • NefroCenter Dialysis Centers

    RECRUITING

    Torre del Greco, 80059, Italy

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