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Tiny virus may hold key to better kidney transplant care

NCT ID NCT05756036

Knowledge-focused Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether levels of a common virus called Torque teno virus (TTV) can help doctors monitor how well a kidney transplant patient's immune system is suppressed. The goal is to find a simple blood test that could predict rejection or infection. Researchers followed 268 kidney transplant recipients and measured TTV levels alongside other markers. If TTV levels prove reliable, this could lead to more personalized immune suppression dosing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test to help doctors balance immune suppression in kidney transplant patients, reducing rejection and infection risks.
What could go wrong
This is an observational study, not a treatment trial, so it cannot prove cause and effect. The virus levels may not reliably predict outcomes in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

268 people

The number who actually took part.

Started

Feb 2022

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All consenting renal transplant recipients in the study period

Ages

16 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All consenting renal transplant recipients in the study period will be included in the study Exclusion Criteria: * no exclusion criteria.

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Conditions

The condition(s) this trial relates to.

acute transplant rejection renal infectious disease transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Immunosuppression Renal transplant failure Renal transplant infection Renal transplant rejection

Contacts and locations

Locations

  • Royal London Hospital

    London, SW4 8FA, United Kingdom

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