Shock therapy for cramps? tiny trial tests nerve zaps for period pain

NCT ID NCT07352982

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive nerve stimulation technique, called transcutaneous tibial nerve stimulation (TTNS), can reduce pain and improve quality of life in women with primary dysmenorrhea (painful periods). Thirty-two women aged 20-25 will receive either TTNS plus standard painkillers or a placebo version plus painkillers for three sessions a week over four weeks. The goal is to see if adding TTNS leads to greater pain relief and lower prostaglandin levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
transcutaneous tibial nerve stimulation (TTNS) plus nonsteroidal anti-inflammatory drugs
What this could lead to
If it works, this could offer a drug-free add-on option to ease period pain and improve daily life for women with primary dysmenorrhea.
What could go wrong
This is a small, early-phase study with only 32 participants, so results may not apply widely. The nerve stimulation is non-invasive, but the placebo group also gets standard painkillers, making it hard to separate the added benefit.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kafrelsheikh University (Faculty of Physical Therapy)

    RECRUITING

    Kafr ash Shaykh, Kafrelsheikh, 33516, Egypt

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