Tryptophan levels may explain why some migraine drugs fail
NCT ID NCT07177885
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at why over 20% of migraine patients don't respond well to triptans, a common migraine medication. Researchers will compare tryptophan and related substances in the blood of 144 people who either respond or don't respond to triptans. The goal is to understand the biological reasons behind treatment failure, which could lead to better personalized migraine care in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors personalize migraine treatments based on a patient's tryptophan levels.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to any immediate changes in care.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU de Clermont-Ferrand
RECRUITINGClermont-Ferrand, France
Contact
Contact Email: •••••@•••••
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