Could Real-World data replace placebos in brain cancer trials?

This study looks at whether a large database of patient health records (Truveta) can be used as a control group for a glioblastoma drug called BPM31510. Glioblastoma is a fast-growing brain tumor, and it is hard to run traditional placebo-controlled trials because the disease is rare and deadly. The researchers will check if the database has enough complete and accurate information on untreated patients to meet FDA standards. This is not a treatment study—it is a data quality check to see if a new way of testing drugs might be possible.