New valve replacement could fix leaky hearts without cutting chest open

NCT ID NCT04433065

Ongoing Disease control Sponsor: Medtronic Cardiovascular Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This study tests a new device that replaces a leaky tricuspid heart valve using a thin tube inserted through a leg vein, avoiding open-heart surgery. It includes 150 people with severe tricuspid regurgitation who are too high-risk for surgery. The goal is to see if the device is safe and works well.

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Conditions

The condition(s) this trial relates to.

tricuspid valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRICUSPID REGURGITATION

Contacts and locations

Locations

Abbott Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Abrazo Arizona Heart Hospital

Phoenix, Arizona, 85016, United States
Aurora Saint Lukes Medical Center

Milwaukee, Wisconsin, 53125, United States
California Pacific Medical Center

San Francisco, California, 94115, United States
Cedars Sinai Medical Center

Los Angeles, California, 90048, United States
Corewell Health

Grand Rapids, Michigan, 49503, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
New York-Presbyterian Hospital Columbia University Medical Center

New York, New York, 10032, United States
OhioHealth Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Oregon Health & Science University Hospital

Portland, Oregon, 97239, United States
Providence Saint Patrick Hospital

Missoula, Montana, 59802, United States
The Christ Hospital

Cincinnati, Ohio, 45242, United States
The Mount Sinai Hospital

New York, New York, 10029, United States
UPMC Pinnacle Harrisburg Campus

Harrisburg, Pennsylvania, 17101, United States
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of Alabama at Birmingham (UAB) Hospital

Birmingham, Alabama, 35233, United States
University of Michigan Health System - University Hospital

Ann Arbor, Michigan, 48109, United States

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