New valve replacement could fix leaky heart without opening chest

NCT ID NCT04433065

First seen Jan 04, 2026 · Last updated May 13, 2026 · Updated 22 times

Summary

This study tests a new device that replaces a leaky tricuspid heart valve using a tube inserted through a leg vein, avoiding open-heart surgery. It includes 150 people with severe valve leakage who are still having symptoms despite medication. The goal is to see if the device is safe and works well.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Abbott Northwestern Hospital

    RECRUITING

    Minneapolis, Minnesota, 55407, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Abrazo Arizona Heart Hospital

    RECRUITING

    Phoenix, Arizona, 85016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Aurora Saint Lukes Medical Center

    RECRUITING

    Milwaukee, Wisconsin, 53125, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • California Pacific Medical Center

    RECRUITING

    San Francisco, California, 94115, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cedars Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Corewell Health

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Emory University Hospital Midtown

    RECRUITING

    Atlanta, Georgia, 30308, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hartford Hospital

    RECRUITING

    Hartford, Connecticut, 06102, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Houston Methodist Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • New York-Presbyterian Hospital Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • OhioHealth Riverside Methodist Hospital

    RECRUITING

    Columbus, Ohio, 43214, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Oregon Health & Science University Hospital

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Providence Saint Patrick Hospital

    RECRUITING

    Missoula, Montana, 59802, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • The Christ Hospital

    RECRUITING

    Cincinnati, Ohio, 45242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • The Mount Sinai Hospital

    RECRUITING

    New York, New York, 10029, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UPMC Pinnacle Harrisburg Campus

    RECRUITING

    Harrisburg, Pennsylvania, 17101, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Alabama at Birmingham (UAB) Hospital

    RECRUITING

    Birmingham, Alabama, 35233, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Michigan Health System - University Hospital

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.