New topical drug could tackle stubborn toenail fungus
NCT ID NCT07065773
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a topical solution called Trichostatin A for mild-to-severe toenail fungus (onychomycosis). About 50 adults with a confirmed fungal infection will apply the drug daily for 4 weeks. Researchers will check safety and whether the fungus clears up using lab tests.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Trichostatin A (topical solution)
What this could lead to
If successful, this could provide a new topical treatment option for stubborn toenail fungus infections.
What could go wrong
This is an early Phase 2 study with only 50 participants, so results may not apply broadly. The treatment may not clear the infection or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Vanda Investigational Site
Fremont, California, 94538, United States
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Vanda Investigational Site
Denver, Colorado, 80210, United States
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Vanda Investigational Site
New Brighton, Minnesota, 55112, United States
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Vanda Investigational Site
Pflugerville, Texas, 78660, United States
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Vanda Investigational Site
Forest, Virginia, 24551, United States