New light therapy takes on stubborn toenail fungus
NCT ID NCT03098342
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two treatments for toenail fungus in 27 Asian adults: a light-activated dye (methylene blue photodynamic therapy) and a medicated nail polish (amorolfine). The goal was to see which worked better and was safer. Participants received either the light treatment or the polish, and doctors used special photos to measure improvement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
methylene blue (used in photodynamic therapy) and amorolfine nail lacquer
What this could lead to
If successful, this could offer a new, non-drug treatment option for stubborn toenail fungus, potentially with fewer side effects than long-term antifungal pills.
What could go wrong
This is a small, completed study with only 27 participants, so results may not apply to everyone. Photodynamic therapy requires multiple clinic visits and may cause temporary pain or redness.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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King Chulalongkorn Memorial Hospital
Bangkok, Bangkok, 10330, Thailand