New inhaled drug aims to help lung patients breathe and move easier

NCT ID NCT07179380

Recruiting now Disease control Sponsor: Insmed Incorporated Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests an inhaled drug called treprostinil palmitil in 344 adults with pulmonary hypertension caused by interstitial lung disease. Participants take the drug or a placebo once daily for 24 weeks. The main goal is to see if the drug helps them walk farther in six minutes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Treprostinil palmitil inhalation powder (a drug inhaled to open blood vessels in the lungs)

What this could lead to

If it works, this could offer a new daily inhaled treatment to help people with PH-ILD walk farther and delay worsening of their condition.

What could go wrong

This is a phase 3 trial, but the drug is still experimental. It may not improve exercise capacity more than placebo, and side effects like cough or throat irritation are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

interstitial lung disease pulmonary hypertension pulmonary hypertension owing to lung disease and/or hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTERSTITIAL LUNG DISEASE PULMONARY HYPERTENSION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ARG001
NOT_YET_RECRUITING

Córdoba, X5003DCE, Argentina
ARG002
NOT_YET_RECRUITING

CiudadAutonoma de Buenos Aires, Buenos Aires, C1280AEB, Argentina
ARG003
NOT_YET_RECRUITING

Río Cuarto, Córdoba Province, X5800AEV, Argentina
ARG004
NOT_YET_RECRUITING

Córdoba, X5000KEH, Argentina
ARG008
NOT_YET_RECRUITING

San Miguel de Tucumán, Tucumán Province, T4000AXL, Argentina
AUS001
NOT_YET_RECRUITING

Camperdown, New South Wales, 2050, Australia
AUS003
NOT_YET_RECRUITING

Westmead, New South Wales, 2145, Australia
AUS005
NOT_YET_RECRUITING

New Lambton Heights, New South Wales, 2305, Australia
AUS006
NOT_YET_RECRUITING

Kingswood, New South Wales, 2747, Australia
AUT002
NOT_YET_RECRUITING

Innsbruck, 6020, Austria
BEL001
NOT_YET_RECRUITING

Anderlecht, 1070, Belgium
BEL002
NOT_YET_RECRUITING

Leuven, Vlaams Brabant, 3000, Belgium
CHE001
NOT_YET_RECRUITING

Basel, 4031, Switzerland
CHE002
NOT_YET_RECRUITING

Zurich, 8091, Switzerland
CZE001
RECRUITING

Prague, 14000, Czechia
DEU003
NOT_YET_RECRUITING

München, Bavaria, 80335, Germany
DEU005
NOT_YET_RECRUITING

Immenhausen, Baden-Wurttemberg, 34376, Germany
DEU006
RECRUITING

München, Bavaria, 80639, Germany
DEU008
NOT_YET_RECRUITING

Bonn, North Rhine-Westphalia, 53127, Germany
DEU009
NOT_YET_RECRUITING

Homburg, Saarland, 66424, Germany
DEU010
RECRUITING

Gauting, 82131, Germany
DEU011
NOT_YET_RECRUITING

Lübeck, Schleswig-Holstein, 23562, Germany
DEU012
NOT_YET_RECRUITING

Stuttgart, Baden-Wurttemberg, 70376, Germany
DNK001
NOT_YET_RECRUITING

Aarhus N, Central Jutland, 8200, Denmark
ESP001
NOT_YET_RECRUITING

Seville, 41009, Spain
ESP002
NOT_YET_RECRUITING

Palma de Mallorca, Balearic Islands, 7120, Spain
ESP003
NOT_YET_RECRUITING

Madrid, 28046, Spain
ESP004
NOT_YET_RECRUITING

Barcelona, 8036, Spain
ESP005
NOT_YET_RECRUITING

L'Hospitalet de Llobregat, Barcelona, 8907, Spain
ESP006
RECRUITING

Madrid, 28041, Spain
ESP007
NOT_YET_RECRUITING

Toledo, 45007, Spain
ESP009
NOT_YET_RECRUITING

Madrid, 28304, Spain
ESP010
NOT_YET_RECRUITING

Majadahonda, Madrid, 28222, Spain
ESP011
NOT_YET_RECRUITING

Santiago de Compostela, 15706, Spain
ESP012
RECRUITING

Barcelona, 8035, Spain
FRA001
NOT_YET_RECRUITING

Poitiers, Vienne, 86000, France
FRA002
RECRUITING

Marseille, Bouches-du-Rhône, 13015, France
FRA003
RECRUITING

Le Kremlin-Bicêtre, Val-de-Marne, 94270, France
FRA004
NOT_YET_RECRUITING

Angers, Maine-et-Loire, 49100, France
FRA006
NOT_YET_RECRUITING

Strasbourg, 67091, France
FRA007
NOT_YET_RECRUITING

Lille, Nord, 59037, France
FRA008
NOT_YET_RECRUITING

Saint Priest En Jarez, Pays de la Loire Region, 42270, France
FRA009
NOT_YET_RECRUITING

Nice, Alpes-Maritimes, 6001, France
FRA010
NOT_YET_RECRUITING

Brest, 29200, France
FRA011
NOT_YET_RECRUITING

Bron, 69500, France
GBR002
NOT_YET_RECRUITING

London, NW3 2QG, United Kingdom
GBR004
NOT_YET_RECRUITING

Sheffield, Yorkshire, S10 2JF, United Kingdom
GBR005
NOT_YET_RECRUITING

Southampton, SO16 6YD, United Kingdom
GBR009
NOT_YET_RECRUITING

London, Greater London, W12 0HS, United Kingdom
GEO001
NOT_YET_RECRUITING

Tbilisi, 0186, Georgia
GEO002
NOT_YET_RECRUITING

Tbilisi, 0144, Georgia
GEO003
RECRUITING

Tbilisi, 0180, Georgia
GEO004
NOT_YET_RECRUITING

Tbilisi, 0159, Georgia
GRC002
NOT_YET_RECRUITING

Athens, Anatoliki Attiki, 106 76, Greece
GRC003
NOT_YET_RECRUITING

Pátrai, Achaia, 26504, Greece
ISR001
NOT_YET_RECRUITING

Haifa, 3436212, Israel
ISR002
NOT_YET_RECRUITING

Jerusalem, Jerusalem, 9112001, Israel
ISR003
NOT_YET_RECRUITING

Petah Tikva, Central District, 4941492, Israel
ISR004
NOT_YET_RECRUITING

Tel Aviv, 6423906, Israel
ISR005
NOT_YET_RECRUITING

Haifa, 3109601, Israel
ITA001
NOT_YET_RECRUITING

Pavia, 27100, Italy
ITA003
NOT_YET_RECRUITING

Roma, 161, Italy
ITA008
NOT_YET_RECRUITING

Milan, 20123, Italy
ITA011
NOT_YET_RECRUITING

Bologna, Emilia-Romagna, 40138, Italy
ITA012
NOT_YET_RECRUITING

Sassari, 07100, Italy
JPN001
NOT_YET_RECRUITING

Sapporo, Hokkaido, 060-8648, Japan
JPN002
NOT_YET_RECRUITING

Narashino-shi, Chiba, 275-0006, Japan
JPN003
NOT_YET_RECRUITING

Shibuya City, Tokyo, 151-8528, Japan
JPN004
RECRUITING

Narita-shi, Chiba, 286-8520, Japan
JPN005
RECRUITING

Nagano, Nagano, 380-0928, Japan
JPN006
NOT_YET_RECRUITING

Nagakute, Aichi-ken, 480-1195, Japan
JPN007
RECRUITING

Yokohama, Kanagawa, 236-0051, Japan
JPN008
NOT_YET_RECRUITING

Kiyose, Tokyo, 204-0023, Japan
JPN010
NOT_YET_RECRUITING

Kyotoshi, Kyoto, 606-8507, Japan
JPN011
NOT_YET_RECRUITING

Hirosaki, Aomori, 036-8563, Japan
JPN013
NOT_YET_RECRUITING

Bunkyo-Ku, Tokyo, 113-8431, Japan
JPN014
NOT_YET_RECRUITING

Chiba, 260-8677, Japan
JPN015
NOT_YET_RECRUITING

Sakai, Osaka, 590-0197, Japan
JPN016
NOT_YET_RECRUITING

Tsukuba, 305-8576, Japan
KOR001
NOT_YET_RECRUITING

Seoul, 03080, South Korea
KOR002
NOT_YET_RECRUITING

Incheon, 21565, South Korea
KOR003
NOT_YET_RECRUITING

Seoul, 6591, South Korea
KOR004
NOT_YET_RECRUITING

Seoul, 3722, South Korea
KOR005
NOT_YET_RECRUITING

Wŏnju, 26426, South Korea
KOR006
NOT_YET_RECRUITING

Seoul, 6351, South Korea
MYS001
NOT_YET_RECRUITING

Kota Bharu, Kelantan, 15586, Malaysia
MYS002
NOT_YET_RECRUITING

Kuching, Sarawak, 93586, Malaysia
MYS003
NOT_YET_RECRUITING

Kuantan, Pahang, 25200, Malaysia
MYS004
NOT_YET_RECRUITING

Alor Star, Kedah, 5460, Malaysia
MYS005
NOT_YET_RECRUITING

Kajang, Selangor, 43000, Malaysia
NZL001
NOT_YET_RECRUITING

Christchurch, Canterbury, 8011, New Zealand
NZL002
NOT_YET_RECRUITING

Dunedin, Otago, 9010, New Zealand
PRT001
NOT_YET_RECRUITING

Lisbon, 1769-001, Portugal
PRT002
NOT_YET_RECRUITING

Almada, Setúbal District, 2805-267, Portugal
ROU001
NOT_YET_RECRUITING

Timișoara, Timiș County, 300310, Romania
ROU002
NOT_YET_RECRUITING

Târgu Mureş, Mureș County, 540136, Romania
TWN001
NOT_YET_RECRUITING

Kaohsiung City, 80756, Taiwan
TWN002
NOT_YET_RECRUITING

Taipei, 10002, Taiwan
TWN003
NOT_YET_RECRUITING

Hsinchu, 300, Taiwan
TWN005
NOT_YET_RECRUITING

Taichung, 40447, Taiwan
TWN006
NOT_YET_RECRUITING

Taipei, 104, Taiwan
USA001
NOT_YET_RECRUITING

Santa Barbara, California, 93105-4349, United States
USA002
NOT_YET_RECRUITING

Kansas City, Kansas, 66160, United States
USA003
RECRUITING

Bend, Oregon, 97701, United States
USA006
RECRUITING

Naples, Florida, 34102-5412, United States
USA008
NOT_YET_RECRUITING

Richmond, Virginia, 23230, United States
USA010
NOT_YET_RECRUITING

Los Angeles, California, 900275969, United States
USA013
NOT_YET_RECRUITING

Philadelphia, Pennsylvania, 19140, United States
USA026
NOT_YET_RECRUITING

St. Petersburg, Florida, 33707-6129, United States