Spinal injection aims to slow ALS in early trial
NCT ID NCT07674667
First seen Jun 29, 2026 · Last updated Aug 06, 2026 · Updated 7 times
Summary
This study tests a single injection of TRCN-1023 into the spinal fluid of adults with ALS. The goal is to see if it is safe and shows early signs of slowing the disease over 24 weeks. Participants are randomly assigned to receive the drug or a placebo, and neither they nor their doctors know which they get.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- TRCN-1023
- What this could lead to
- If successful, this could point toward a new treatment that slows or stops the progression of ALS.
- What could go wrong
- This is an early-phase trial with only 30 participants, so results may not apply to all ALS patients. The drug may not show benefit or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
TUM Klinikum Rechts der Isar
RECRUITINGMunich, Germany
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University Medical Center Utrecht
RECRUITINGUtrecht, 3508 GA, Netherlands
Contact Email: •••••@•••••
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