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Tiny study aims to find safer clotting drugs for trauma patients

NCT ID NCT07290634

Recruiting now Knowledge-focused Sponsor: Zeliha Alicikus Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks back at medical records of 4 severely injured trauma patients who needed large blood transfusions. It compares two drugs that help blood clot—prothrombin complex concentrate and recombinant activated factor VIIa—to see which causes fewer dangerous blood clots and other complications. The goal is to learn which drug might be safer for these critically ill patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Prothrombin complex concentrate and recombinant activated factor VIIa
What this could lead to
If successful, this could help doctors choose the safest blood-clotting drug for trauma patients needing massive transfusions, potentially reducing complications.
What could go wrong
This is a very small, early retrospective study with only 4 participants, so results may not apply broadly. The study only observes past events, so it cannot prove cause and effect.

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Conditions

The condition(s) this trial relates to.

injury thrombocytopenia Thromboembolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MASSIVE BLOOD TRANSFUSION; THROMBOCYTOPENIA THROMBOEMBOLUS TRAUMA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UF Health Jacksonville (Shands Hospital)

    RECRUITING

    Jacksonville, Florida, 32209, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UF Health Jacksonville (Shands Hospital)

    RECRUITING

    Jacksonville, Florida, 32218, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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