New program aims to cut overdose risk for women leaving prison

NCT ID NCT06651528

ENROLLING_BY_INVITATION Disease control Sponsor: Michele Staton Source: ClinicalTrials.gov ↗

First seen Nov 10, 2025 · Last updated Jun 23, 2026 · Updated 24 times

Summary

This study tests a trauma-informed program called TRUST for women leaving prison who have substance use disorder. The program includes individual and group sessions to build skills and support recovery. Researchers will measure changes in substance use and trauma symptoms. The goal is to reduce overdose risk during the transition back to the community.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Chillicothe Correctional Center

    Chillicothe, Missouri, 64601, United States

  • Franklin County Regional Jail

    Frankfort, Kentucky, 40601, United States

  • Kentucky Correctional Institution for Women

    Pewee Valley, Kentucky, 40056, United States

  • Women's Eastern Reception, Diagnostic and Correctional Center

    Vandalia, Missouri, 63382, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

behavioral intervention (TRUST program based on Trust-Based Relational Intervention)

What this could lead to

If successful, this could provide an effective, trauma-informed approach to reduce overdose risk and support recovery for women re-entering the community from prison.

What could go wrong

This is an early-stage study (phase not specified) with 264 participants, so results may not apply broadly. The intervention is behavioral, so outcomes depend on individual engagement and community support.

Conditions

The condition(s) this trial relates to.

Drug Overdose substance-related disorder poisoning prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.