Breast cancer drugs take on rare tumors in new trial
NCT ID NCT05786716
First seen Jan 11, 2026 · Last updated Apr 25, 2026 · Updated 19 times
Summary
This study tests two drugs, trastuzumab and pertuzumab, already approved for breast cancer, in people with rare cancers that have a specific genetic change called HER2 amplification or mutation. About 30 adults, children, and teens with these rare cancers will receive the drug combination. The goal is to see if the drugs can shrink tumors or stop them from growing for at least 24 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Addenbrooke's Hospital
RECRUITINGCambridge, CB2 OQQ, United Kingdom
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Alder Hey Hospital
RECRUITINGLiverpool, L14 5AB, United Kingdom
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Belfast City Hospital
RECRUITINGBelfast, BT9 7AB, United Kingdom
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Birmingham Children's Hospital
NOT_YET_RECRUITINGBirmingham, United Kingdom
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Bristol Haematology and Oncology Centre
RECRUITINGBristol, BS2 8ED, United Kingdom
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Bristol Royal Hospital for Children
RECRUITINGBristol, BS2 8BJ, United Kingdom
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Cardiff Children's Hospital
NOT_YET_RECRUITINGCardiff, CF14 4XW, United Kingdom
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Churchill Hospital
RECRUITINGOxford, OX3 7LE, United Kingdom
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Clatterbridge Cancer Centre
RECRUITINGMetropolitan Borough of Wirral, CH63 4JY, United Kingdom
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Freeman Hospital
RECRUITINGNewcastle, NE7 7DN, United Kingdom
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Great North Children's Hospital
RECRUITINGNewcastle, NE1 4LP, United Kingdom
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Great Ormond Street Hospital
RECRUITINGLondon, WC1N 3JH, United Kingdom
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Guy's Hospital
RECRUITINGLondon, SE1 9RT, United Kingdom
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John Radcliffe Hospital
RECRUITINGOxford, OX3 9DU, United Kingdom
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Leicester Royal Infirmary
RECRUITINGLeicester, LE1 5WW, United Kingdom
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Royal Hospital for Children Glasgow
RECRUITINGGlasgow, G51 4TF, United Kingdom
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Royal Manchester Children's Hospital
NOT_YET_RECRUITINGManchester, M13 9WL, United Kingdom
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Sheffield's Children's Hospital
RECRUITINGSheffield, S10 2TH, United Kingdom
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Southampton General Hospital
RECRUITINGSouthampton, SO16 6YD, United Kingdom
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The Beatson Hospital
RECRUITINGGlasgow, G12 OYN, United Kingdom
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The Christie Hospital
RECRUITINGManchester, M20 4BX, United Kingdom
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The Royal Marsden Hospital
RECRUITINGSutton, SM2 5PT, United Kingdom
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University College London Hospital
RECRUITINGLondon, NW1 2BU, United Kingdom
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University Hospital Birmingham
RECRUITINGBirmingham, B15 2TT, United Kingdom
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Velindre Cancer Centre
RECRUITINGCardiff, CF14 2TL, United Kingdom
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Western General Hospital
RECRUITINGEdinburgh, EH4 2XU, United Kingdom
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Weston Park Hospital
RECRUITINGSheffield, S10 2SJ, United Kingdom
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Conditions
Explore the condition pages connected to this study.