Breathing tube shape may reduce pneumonia risk in ICU patients

NCT ID NCT01948635

Completed Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a specially shaped cuff on breathing tubes could reduce the amount of stomach fluid that leaks into the lungs of critically ill patients on ventilators. Researchers measured pepsin levels (a stomach enzyme) in 326 adults to track leakage. The goal was to see if this tube design could help prevent lung infections.

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Conditions

The condition(s) this trial relates to.

Critical Illness Pneumonia, Ventilator-Associated

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS MECHANICAL VENTILATION COMPLICATION VENTILATOR ASSOCIATED PNEUMONIA

Contacts and locations

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Locations

Centre Hospitalie

Tourcoing, France
Centre Hospitalier

Dunkirk, France
Centre Hospitalier

Lens, France
Centre Hospitalier

Valenciennes, France
Centre Hospitalier St Philibert

Lomme, France
Centre Hospitalier Universitaire

Rouen, France
Centre hospitalier

Roubaix, France
ICU, Salengro Hospital, University Hospital of Lille

Lille, Nord, 59035, France
centre Hospitalier

Boulogne-sur-Mer, France