New inhaled drug aims to ease COPD breathing

NCT ID NCT07147946

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This Phase 3 trial tests an inhaled drug called TQC3721 in 666 people with moderate-to-severe COPD. The drug works by reducing inflammation and opening airways. Participants will inhale the drug or a placebo daily for up to 24 weeks to see if it improves lung function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
TQC3721 suspension for inhalation (a PDE3/4 inhibitor)
What this could lead to
If successful, this could provide a new inhaled treatment option to help control COPD symptoms and improve lung function.
What could go wrong
This is a Phase 3 trial, but results may not show significant benefit over placebo. Side effects from the drug are possible, and it is not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Hospital of Jining Medical University

    Jining, Shandong, 272029, China

  • Affiliated Hospital of North Sichuan Medical College

    Nanchong, Sichuan, 637000, China

  • Baoji Central Hospital

    Baoji, Shanxi, 721008, China

  • Baotou Central Hospital

    Baotou, Inner Mongolia, 14000, China

  • Binzhou People's Hospital

    Binzhou, Shandong, 256610, China

  • Bozhou People's Hospital

    Bozhou, Anhui, 236805, China

  • Cangzhou Hospital of Integrated TCM- WM·HEBEI

    Cangzhou, Hebei, 61013, China

  • Central Hospital of Dalian University of Technology

    Dalian, Liaoning, 116000, China

  • Changzhi People's Hospital

    Changzhi, Shanxi, 46000, China

  • Chaohu Hospital of Anhui Medical University

    Hefei, Anhui, 238000, China

  • Chengdu Second People's Hospital

    Chengdu, Sichuan, 610017, China

  • Chifeng Municipal Hospital

    Chifeng, Inner Mongolia, 24000, China

  • Chizhou People's Hospital

    Chizhou, Anhui, 247000, China

  • Chongqing University Three Gorges Hospital

    Chongqing, Chongqing Municipality, 404000, China

  • Daqing Longnan Hospital

    Daqing, Heilongjiang, 163000, China

  • Dongyang People's Hospital

    Jinhua, Zhejiang, 322100, China

  • Fujian Medical University Union Hospital

    Fuzhou, Fujian, 350000, China

  • Fuling Hospital Affiliated to Chongqing University

    Chongqing, Chongqing Municipality, 408099, China

  • Gansu Provincial Hospital

    Lanzhou, Gansu, 730099, China

  • Guizhou Provincial People's Hospital

    Guiyang, Guizhou, 550000, China

  • Hebei Medical University Third Hospital

    Shijiazhuang, Hebei, 65799, China

  • Hebei PetroChina Central Hospital

    Langfang, Hebei, 65000, China

  • Heze Municipal Hospital

    Heze, Shandong, 274031, China

  • Huizhou Central People's Hospital

    Huizhou, Guangdong, 516000, China

  • Hunan Provincial People's Hospital

    Changsha, Hunan, 410001, China

  • Inner Mongolia Medical University Affiliated Hospital

    Hohhot, Inner Mongolia, 10000, China

  • Jiangxi Provincial People's Hospital

    Nanchang, Jiangxi, 330006, China

  • Jiangyin Hospital of Traditional Chinese Medicine

    Wuxi, Jiangsu, 214400, China

  • Jiaozuo Second People's Hospital

    Jiaozuo, Henan, 454001, China

  • Jinhua municipal central hospital

    Jinhua, Zhejiang, 321000, China

  • Jiujiang First People's Hospital

    Jiujiang, Jiangxi, 332000, China

  • Longgang District People's Hospital of Shenzhen

    Shenzhen, Guangdong, 518000, China

  • Mianyang Central Hospital

    Mianyang, Sichuan, 621000, China

  • Mianyang Hospital of Traditional Chinese Medicine

    Mianyang, Sichuan, 621000, China

  • Nanjing Jiangning Hospital

    Nanjing, Jiangsu, 21100, China

  • Peking University Shenzhen Hospital

    Shenzhen, Guangdong, 518000, China

  • Peolpe's Hospital Of Chongqing Banan District

    Chongqing, Chongqing Municipality, 400054, China

  • Puyang Oilfield General Hospital

    Puyang, Henan, 457001, China

  • Qinghai Provincial People's Hospital

    Xining, Qinghai, 810007, China

  • Qiqihar First Hospital

    Qiqihar, Heilongjiang, 161005, China

  • Ruijin Hospital, Shanghai Jiaotong University School of Medicine

    Shanghai, Shanghai Municipality, 200023, China

  • Shanghai General Hospital

    Shanghai, Shanghai Municipality, 200080, China

  • Shaoxing People's Hospital

    Shaoxing, Zhejiang, 312000, China

  • Shengjing Hospital of China Medical University

    Shenyang, Liaoning, 110021, China

  • Subei People's Hospital of Jiangsu province

    Yangzhou, Jiangsu, 225001, China

  • Suining Central Hospital

    Suining, Sichuan, 629099, China

  • Taizhou Central Hospital

    Taizhou, Zhejiang, 318000, China

  • The Central Hospital of Yongzhou

    Yongzhou, Hunan, 425002, China

  • The Eighth Affiliated Hospital of Southern Medical University(The First people's Hospital of Shunde )

    Foshan, Guangdong, 528300, China

  • The Fifth People's Hospital of Wuxi

    Wuxi, Jiangsu, 214001, China

  • The First Affiliated Hospital of Chengdu Medical College

    Chengdu, Sichuan, 610000, China

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400010, China

  • The First Affiliated Hospital of Hainan Medical University

    Haikou, Hainan, 570102, China

  • The First Affiliated Hospital of Harbin Medical University

    Harbin, Heilongjiang, 150001, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, 330006, China

  • The First Affiliated Hospital of Ningbo University

    Ningbo, Zhejiang, 315000, China

  • The First Affiliated Hospital of Shihezi University

    Shihezi, Xinjiang, 832008, China

  • The First Hospital of Lanzhou University

    Lanzhou, Gansu, 730000, China

  • The First Hospital of Qinhuangdao

    Qinhuangdao, Hebei, 66000, China

  • The First People's Hospital of Shangqiu

    Shangqiu, Henan, 476100, China

  • The Second Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325000, China

  • The Second Hospital of Jiaxing

    Jiaxing, Zhejiang, 314000, China

  • The first hospital of Jilin University

    Changchun, Jilin, 130000, China

  • Tianjin 4th Center Hospital

    Tianjin, Tianjin Municipality, 300140, China

  • Tianjin Medical University General Hospital

    Tianjin, Tianjin Municipality, 300052, China

  • Weifang NO.2 People's Hospital

    Weifang, Shandong, 261041, China

  • West China Hospital of Sichuan University

    Chengdu, Sichuan, 610044, China

  • Xi'an International Medical Center Hospital

    Xi'an, Shaanxi, 710100, China

  • Xiangya Hospital of Central South University

    Changsha, Hunan, 410028, China

  • Xuzhou Central Hospital

    Xuzhou, Jiangsu, 221009, China

  • Yan'an University Xianyang Hospital

    Xianyang, Shaanxi, 712000, China

  • Yangquan coal Industry(Group) General Hospital

    Yangquan, Shanxi, 45000, China

  • Yantai Yuhuangding Hospital

    Yantai, Shandong, 264099, China

  • Yichang Central People's Hospital

    Yichang, Hubei, 443003, China

  • Yixing People's Hospital

    Yixing, Jiangsu, 225000, China

  • Zhangzhou Municipal Hospital of Fujian Province

    Zhangzhou, Fujian, 363000, China

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