New antibody drug aims to cut COPD attacks in half

NCT ID NCT06789289

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests TQC2938, a lab-made antibody, in 256 people with moderate to severe COPD. The goal is to see if the drug can reduce the number of serious flare-ups over 24 weeks compared to a placebo. Participants receive injections and are monitored for safety and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TQC2938 (a lab-made antibody that blocks certain signals in the body)

What this could lead to

If it works, this could lead to a new treatment that reduces the number of serious COPD flare-ups, helping patients breathe easier and stay out of the hospital.

What could go wrong

This is a mid-stage trial with only 256 people, so results may not apply to everyone. The drug is still experimental, and side effects or lack of benefit are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC OBSTRUCTIVE PULMONARY DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Hospital Of ChengDu University

    Chengdu, Sichuan, 610081, China

  • Affiliated Hospital of Jiangsu University

    Zhenjiang, Jiangsu, 212050, China

  • An Hui Chest Hospital

    Hefei, Anhui, 230000, China

  • Cangzhou Central Hospital

    Cangzhou, Hebei, 061000, China

  • China-Japan Friendship Hospital

    Beijing, Beijing Municipality, 100029, China

  • Henan Chest Hospital

    Zhengzhou, Henan, 450000, China

  • Heze Municipal Hospital

    Heze, Shandong, China

  • Jiangmen Central Hospital

    Jiangmen, Guangdong, 529000, China

  • Jiangxi Provincal People's Hospital

    Nanchang, Jiangxi, 330000, China

  • Jinhua Municipal Centeral Hospital Medical Group

    Jinhua, Zhejiang, 321000, China

  • Leshan People's Hospital

    Leshan, Sichuan, 614099, China

  • Linfen Central Hospital

    Linfen, Shanxi, 041099, China

  • Liuzhou municipal liutie central hospital

    Liuzhou, Guangxi, 545007, China

  • Meihekou Central Hospital

    Meihekou, Jilin, 135000, China

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034, China

  • Peolpe's Hospital Of Chongqing Banan District

    Chongqing, Chongqing Municipality, 400054, China

  • Puyang Oilfield General Hospital

    Puyang, Henan, 457001, China

  • Shanghai JiaoTong University of medicine Ruijin Hospital

    Shanghai, Shanghai Municipality, 20025, China

  • Shanghai Pulmonary Hospital

    Shanghai, Shanghai Municipality, 200433, China

  • Shaoyang Central Hospital

    Shaoyang, Hunan, 422000, China

  • Shunde Hospital Of Southern Medical University

    Foshan, Guangdong, 528308, China

  • Siping Central People's Hospital

    Siping, Jilin, 136099, China

  • Suining Central Hospital

    Suining, Sichuan, 629000, China

  • Taizhou Hospital Of Zhejiang Province

    Taizhou, Zhejiang, 318000, China

  • The 2th School of Medicine ,WMU/The 2th affiliated Hospital and Yuying Children's Hospital of WMU

    Wenzhou, Zhejiang, 325027, China

  • The Affiliated Hospital of Mongolia Medical College

    Hohhot, Inner Mongolia, 010000, China

  • The First Affiliated Hospital of Jiamusi University

    Jiamusi, Heilongjiang, 154003, China

  • The First Affiliated Hospitial Of Ningbo University

    Ningbo, Zhejiang, 315211, China

  • The First Hospital of Qiqihar

    Qiqihar, Heilongjiang, 161005, China

  • The First People' Hospital Of YuLin

    Yulin, Guangxi, 537000, China

  • The First People's Hospital of Xinxiang City

    Xinxiang, Henan, 453000, China

  • The Fourth Central Hospital of Tianjin

    Tianjin, Tianjin Municipality, 300140, China

  • The Third People's Hospital of Xinjiang Uygur Autonomous Region

    Ürümqi, Xinjiang, 830091, China

  • The second hospital of hebei medical university

    Shijiazhuang, Heibei, 05000, China

  • The second xiangya hospital of central south university

    Changsha, Hunan, 410011, China

  • Tianjin Medical University General Hospital

    Tianjin, Tianjin Municipality, 300041, China

  • Weifang NO.2 People' Hospital

    Weifang, Shandong, 261041, China

  • Xi'An International Medicl Center Hospital

    Xi’an, Shanxi, 710061, China

  • Xingtai People's Hospital

    Xingtai, Hebei, 54000, China

  • Yongcheng People's Hospital

    Yongcheng, Henan, 476600, China