New antibody injection aims to tame COPD Flare-Ups
NCT ID NCT06707883
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests an injection called TQC2731 in 258 adults with moderate-to-severe COPD. The drug blocks a protein linked to airway inflammation. Researchers will measure how well it reduces the number of moderate or severe flare-ups over 24 weeks compared to a placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
TQC2731 injection (a monoclonal antibody that blocks TSLP, a protein involved in airway inflammation)
What this could lead to
If successful, this could lead to a new treatment option that reduces the number of serious COPD flare-ups and improves lung function.
What could go wrong
This is an early Phase 2 trial with only 258 participants, so results may not apply to all COPD patients. The drug may not work better than placebo or could have side effects not yet seen.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Affiliated Hospital Of ChengDu University
Chengdu, Sichuan, 610081, China
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Affiliated Hospital of Jiangsu University
Zhenjiang, Jiangsu, 212050, China
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Affiliated Qingyuan Hospital,Guangzhou Medical University,Qingyuan People's Hospital
Qingyuan, Guangdong, 511699, China
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Benxi Central Hospital
Benxi, Liaoning, 117000, China
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Cangzhou Central Hospital
Cangzhou, Hebei, 611011, China
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Capital Medical University Beijing Chaoyang Hospital
Beijing, Beijing Municipality, 100020, China
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Changsha First Hospital
Changsha, Hunan, 410005, China
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China-Japan Friendship Hospital
Beijing, Beijing Municipality, 100029, China
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General Hospital of Anshan Iron and Steel Group Corporation
Anshan, Liaoning, 114000, China
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General Hospital of Tianjin Medical University
Tianjin, Tianjin Municipality, 300070, China
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Guangyuan Central Hospital
Guangyuan, Sichuan, 628017, China
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Henan Chest Hospital
Zhengzhou, Henan, 450000, China
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Heze Municipal Hospital
Heze, Shandong, 274000, China
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Huainan Dongfang Hospital Group General Hospital
Huainan, Anhui, 232033, China
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Inner Mongolia Autonomous Region People's Hospital
Hohhot, Inner Mongolia, 010000, China
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Jianghan University Affiliated Hospital (Wuhan Sixth Hospital)
Wuhan, Hubei, 430014, China
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Jiangmen Central Hospital
Jiangmen, Guangdong, 529000, China
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Jiangxi Provincial People's Hospital
Nanchang, Jiangxi, 330006, China
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Jiangyin Hospital of Traditional Chinese Medicine
Jiangyin, Jiangsu, 214400, China
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Jiaozuo Second People's Hospital
Jiaozuo, Henan, 454150, China
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Jiaxing Second Hospital
Jiaxing, Zhejiang, 314000, China
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Leshan People's Hospital
Leshan, Sichuan, 614099, China
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Linyi People's Hospital
Linyi, Shandong, 276005, China
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Meishan People's Hospital
Meishan, Sichuan, 620000, China
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Nanxishan Hospital of Guangxi Zhuang Autonomous
Guilin, Guangxi, 541002, China
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Puyang Oilfield General Hospital
Puyang, Henan, 457001, China
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Qingdao Municipal Hospital
Qingdao, Shandong, 266011, China
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Shanghai General Hospital
Shanghai, Shanghai Municipality, 200080, China
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Shanghai JiaoTong University of medicine Ruijin Hospital
Shanghai, Shanghai Municipality, 20025, China
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Shanghai Pulmonary Hospital
Shanghai, Shanghai Municipality, 200433, China
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Shengjing Hospital of China Medical University
Shenyang, Liaoning, 110004, China
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Shunde Hospital Of Southern Medical University
Foshan, Guangdong, 528308, China
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Suining Central Hospital
Suining, Sichuan, 629000, China
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Taizhou Central Hospital Central Hospital
Taizhou, Zhejiang, 318000, China
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The 2th School of Medicine ,WMU/The 2th affiliated Hospital and Yuying Children's Hospital of WMU
Wenzhou, Zhejiang, 325027, China
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The Affiliated Hospital of Inner Mongolia Medical University
Hohhot, Inner Mongolia, 10000, China
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The Fifth People's Hospital of Wuxi
Wuxi, Jiangsu, 214001, China
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The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, 510120, China
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The First Affiliated Hospital of Henan University of Science & Technology
Luoyang, Henan, 471003, China
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The First Affiliated Hospital of Shihezi University
Shihezi, Xinjiang, 832000, China
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The First Affiliated Hospital of Xinjiang Medical University
Ürümqi, Xinjiang, 831400, China
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The First Hospital of Jilin University
Changchun, Jilin, 130021, China
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The First Hospital of Lanzhou University
Lanzhou, Gansu, 730000, China
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The First People' Hospital Of YuLin
Yulin, Guangxi, 537000, China
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The First People's Hospital of Chuzhou
Chuzhou, Anhui, 239001, China
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The Fourth Central Hospital of Tianjin
Tianjin, Tianjin Municipality, 300140, China
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The Second Hospital of Hebei Medical University
Shijiazhuang, Hebei, 050000, China
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The Third Xiangya Hospital of Central South University
Changsha, Hunan, 410013, China
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The second hospital of ANHUI medical university
Hefei, Anhui, 230601, China
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Weifang NO.2 People' Hospital
Weifang, Shandong, 261041, China
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Wuhan Central Hospital
Wuhan, Hubei, 430014, China
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Xiangtan County People's Hospital
Xiangtan, Hunan, 411228, China
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Xiangya Hospital Zhuzhou Central South University
Zhuzhou, Hunan, 412007, China
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Xiangya Hospital of Central South University
Changsha, Hunan, 410008, China
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Xinyu People'S Hospital
Xinyu, Jiangxi, 338000, China
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XuZhou Central Hospital
Xuzhou, Jiangsu, 221000, China
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Yichang Central People's Hospital
Yichang, Hubei, 443003, China
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Yixing People'S Hospital
Wuxi, Jiangsu, 214200, China
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Zhongshan City People's Hospital
Zhongshan, Guangdong, 528403, China
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Zunyi Medical University Affiliated Hospital
Zunyi, Guizhou, 563000, China