New surgery aims to cut pancreatic leak and diabetes risk
NCT ID NCT07360119
First seen Jun 26, 2026 · Last updated Jun 30, 2026 · Updated 3 times
Summary
This study tests a surgery called total pancreatectomy with islet autotransplantation (TPIAT) in 30 adults with certain pancreatic tumors who are at high risk for a dangerous leak after standard surgery. The procedure removes the entire pancreas and transplants the insulin-making cells into the liver to help prevent severe diabetes. Researchers will track complications, hospital stay length, and how well the transplanted cells work to see if this approach is safe and feasible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Total pancreatectomy with islet autotransplantation (TPIAT) – a surgery to remove the pancreas and transplant its insulin-making cells into the liver
What this could lead to
If successful, this approach could offer a safer surgical option for patients with certain pancreatic tumors, reducing the chance of a dangerous pancreatic leak and lowering the risk of severe diabetes after surgery.
What could go wrong
This is a very early, small study (30 people) with no comparison group, so results may not apply broadly. The surgery is major and carries risks like infection, bleeding, and the transplanted cells may not work well enough to prevent diabetes.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
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The condition terms exactly as the trial's registrant entered them.
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