Menthol and copaiba cream put to the test for joint pain relief

NCT ID NCT07767669

First seen Aug 17, 2026 ยท Last updated Aug 17, 2026

Summary

This study tests whether a cream made with L-menthol and balsam copaiba oil can reduce symptoms of arthritis, joint pain, and muscle pain. Adults aged 20 to 65 with mild-to-moderate joint discomfort apply the cream or a placebo to affected areas three times daily for seven days. Researchers measure changes in pain, stiffness, and quality of life through questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
A topical cream containing L-menthol and balsam copaiba oil, applied to affected joints three times daily for seven days.
What this could lead to
If effective, this cream could offer a simple, non-drug option for easing everyday joint and muscle discomfort.
What could go wrong
The trial is small and short, and results may not apply to everyone. The cream may not outperform the placebo, and individual responses can vary.

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Conditions

The condition(s) this trial relates to.

Arthralgia arthritic joint disease Musculoskeletal Pain Myalgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Citruslabs

    Las Vegas, Nevada, 89101, United States

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