Could an antidepressant ease chronic back pain?

NCT ID NCT07709416

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This trial investigates whether the antidepressant toludesvenlafaxine can reduce pain in adults with chronic non-specific low back pain. Participants receive either the drug plus routine care or routine care alone for three months. The study measures changes in pain intensity and function to see if the drug offers additional relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an antidepressant drug called toludesvenlafaxine
What this could lead to
If it works, this could offer a new treatment option for chronic low back pain, especially for people who haven't found relief with standard care.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. The drug may cause side effects or prove no better than usual care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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