Vitamin e derivative tested to stall liver failure in cirrhosis patients

NCT ID NCT02581085

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 21 times

Summary

This study tests whether a natural compound called tocotrienol (a form of vitamin E) can slow the worsening of end-stage liver disease in 70 adults with cirrhosis. Participants take either tocotrienol capsules or a placebo twice daily for 3 years. The goal is to see if the treatment prevents rises in a key liver score (MELD) and reduces complications like liver failure or need for transplant.

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Contacts and locations

Locations

  • IU Health Unviersity Hospital

    Indianapolis, Indiana, 46202, United States

Conditions

Explore the condition pages connected to this study.