Brain zaps for stubborn OCD: new hope for Therapy-Resistant patients

NCT ID NCT05331937

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a non-invasive brain stimulation technique called TMS for adults with obsessive-compulsive disorder (OCD) who did not improve enough with standard exposure therapy. 250 participants will receive either real or sham TMS combined with therapy for 5-7 weeks. The goal is to see if TMS can reduce OCD symptoms and improve quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

obsessive-compulsive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam UMC, location VU Medical Center

    RECRUITING

    Amsterdam, North Holland, 1081 HZ, Netherlands

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GGZ inGeest

    RECRUITING

    Amsterdam, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maastricht UMC+

    NOT_YET_RECRUITING

    Maastricht, Netherlands

    Contact Email: •••••@•••••

  • Mondriaan

    NOT_YET_RECRUITING

    Maastricht, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Neurocare

    NOT_YET_RECRUITING

    Eindhoven, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Neurocare

    NOT_YET_RECRUITING

    Groningen, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ProPersona

    NOT_YET_RECRUITING

    Nijmegen, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Radboudumc

    NOT_YET_RECRUITING

    Nijmegen, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••