New anesthesia strategy aims to prevent dangerous blood pressure drops in elderly surgery patients

NCT ID NCT07328958

Recruiting now Symptom relief Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving anesthesia in carefully adjusted doses, rather than fixed amounts, can reduce dangerously low blood pressure in people aged 65 and older having laparoscopic abdominal surgery. The trial will enroll 500 participants and use two drugs, ciprofol and remifentanil, with dosing guided by brain activity monitoring. The goal is to see if this personalized approach leads to fewer episodes of low blood pressure during surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ciprofol and remifentanil
What this could lead to: If it works, this could lead to a safer way to give anesthesia to older adults, reducing complications from low blood pressure during surgery.
What could go wrong: This is a single trial with 500 participants, and results may not apply to all surgeries or patients. The approach is still experimental and may not significantly reduce risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOTENSION DURING SURGERY

Contacts and locations

Locations

Sixth Affiliated Hospital, Sun Yat-sen University
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510655, China
Sixth Affiliated Hospital, Sun Yat-sen University
RECRUITING

Guangzhou, Guangdong, 510655, China

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