Jaw surgery breakthrough: common drug may eliminate need for dangerous anesthesia technique

NCT ID NCT05474027

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving tranexamic acid (TXA) during jaw surgery can reduce the need for deliberate hypotensive anesthesia (DHA), a technique that lowers blood pressure to control bleeding but carries risks like stroke or kidney injury. Researchers studied 115 patients to see if TXA alone could keep the surgical field clear and blood loss low. The goal is to make surgery safer by avoiding DHA when possible.

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Conditions

The condition(s) this trial relates to.

Blood Loss, Surgical

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UAB Hospital-Highlands

    Birmingham, Alabama, 35205, United States