Scientists expose volunteers to tick bites to unlock vaccine secrets
NCT ID NCT05036707
First seen May 02, 2026 · Last updated Jun 22, 2026 · Updated 6 times
Summary
This study looks at how healthy people's skin and immune system respond to tick bites. Researchers will place clean, lab-bred ticks on volunteers' skin and take small skin samples and blood to track changes. The goal is to understand tick resistance and help design future vaccines against tick-borne diseases like Lyme disease.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could help scientists develop vaccines that prevent tick-borne diseases like Lyme disease.
What could go wrong
This is an early-stage study with only 60 healthy volunteers, so results may not apply to everyone. The goal is to understand immune responses, not to test a treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.