Skipping thyroid ultrasound after PET may be safe, study suggests
NCT ID NCT07255482
First seen Jun 25, 2026 · Last updated Aug 11, 2026 · Updated 3 times
Summary
This study examines whether patients who have a thyroid nodule found on a PET scan can safely skip a follow-up ultrasound without affecting their survival. Researchers will compare death rates over 7 years between those who had an ultrasound within 3 months and those who did not. The study uses medical records from 5,000 adults in the Mass General Brigham health system. If skipping ultrasound proves non-inferior, it could reduce unnecessary procedures and patient anxiety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Thyroid ultrasound
- What this could lead to
- If this study shows that skipping ultrasound does not increase death risk, it could reduce unnecessary procedures and anxiety for many patients.
- What could go wrong
- This is an observational study using existing medical records, not a controlled trial. Results may be influenced by other factors and cannot prove cause and effect.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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