UK doctors trial tiny particle blockage to shrink thyroid lumps

NCT ID NCT07046546

Recruiting now Disease control Sponsor: Royal Berkshire NHS Foundation Trust Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study will test the safety of thyroid artery embolization (TAE) in 10 UK patients with benign thyroid nodules or goitre. TAE is a minimally invasive procedure that blocks blood flow to the thyroid gland using tiny particles, causing it to shrink. The goal is to see if it can be safely introduced in the UK, with future larger trials planned to compare it to standard treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Thyroid artery embolization (TAE) - a minimally invasive procedure that blocks thyroid arteries with tiny particles to shrink the gland
What this could lead to: If successful, this could offer a new, less invasive treatment option for people with large thyroid nodules who cannot have surgery or other standard treatments.
What could go wrong: This is a very small pilot study with only 10 patients, focused on safety, not effectiveness. The procedure is new to the UK and may not work as well as hoped or could have unexpected side effects.

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Conditions

The condition(s) this trial relates to.

benign thyroid gland neoplasm goiter Graves disease nodular goiter Thyroid Nodule

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GOITRE GRAVES DISEASE THYROID NODULE (BENIGN)

Contacts and locations

Locations

Royal Berkshire Hospital
RECRUITING

Reading, United Kingdom

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