Could a spice compound ease diabetic nerve pain?
NCT ID NCT07313111
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding thymoquinone, a compound from black seed oil, to the standard pain drug pregabalin could better relieve nerve pain in people with diabetes. Fifty adults with diabetic peripheral neuropathy took both treatments daily for two months. Researchers measured pain levels, nerve function, and markers of inflammation and oxidative stress to see if the combination offered extra benefit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- thymoquinone (a compound from black seed oil) and pregabalin
- What this could lead to
- If it works, this could point toward a simple supplement-based way to boost pain relief and nerve health for people with diabetic neuropathy.
- What could go wrong
- This is a small, completed phase 4 trial with only 50 participants. Results may not apply to everyone, and the supplement's long-term safety or benefit is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hawler medical university, Galyawa diabetic center and Neurophysiology department of hawler psychiatric hospital
Erbil, IRAQ, 44001, Iraq
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can simple foot exercises prevent falls in diabetics?
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- Scientists hunt for blood clues to spot diabetic nerve pain early