Could a spice compound ease diabetic nerve pain?
NCT ID NCT07313111
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding thymoquinone, a compound from black seed oil, to the standard pain drug pregabalin could better relieve nerve pain in people with diabetes. Fifty adults with diabetic peripheral neuropathy took both treatments daily for two months. Researchers measured pain levels, nerve function, and markers of inflammation and oxidative stress to see if the combination offered extra benefit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
thymoquinone (a compound from black seed oil) and pregabalin
What this could lead to
If it works, this could point toward a simple supplement-based way to boost pain relief and nerve health for people with diabetic neuropathy.
What could go wrong
This is a small, completed phase 4 trial with only 50 participants. Results may not apply to everyone, and the supplement's long-term safety or benefit is not yet proven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hawler medical university, Galyawa diabetic center and Neurophysiology department of hawler psychiatric hospital
Erbil, IRAQ, 44001, Iraq