Thumb arthritis surgery showdown: which operation offers faster relief?

NCT ID NCT07552831

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two surgical treatments for thumb arthritis: a prosthetic joint replacement (arthroplasty) versus removal of a small bone at the thumb base (trapeziectomy). Researchers will enroll 64 adults aged 18-69 with thumb arthritis that hasn't improved with non-surgical treatments. Participants will be randomly assigned to one of the two surgeries and followed for up to 10 years to track pain, function, and implant durability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
surgery (prosthetic joint replacement or bone removal)
What this could lead to
If successful, this could show that prosthetic joint replacement offers faster pain relief and better function than the standard bone-removal surgery for thumb osteoarthritis.
What could go wrong
This is a small, early-stage trial with only 64 participants, so results may not apply to everyone. Prosthetic implants can loosen or fail over time, requiring additional surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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