Thumb arthritis surgery showdown: simple removal vs. reconstruction

NCT ID NCT03858946

Completed Symptom relief Sponsor: University of Southern Denmark Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two surgeries for severe thumb arthritis: simple removal of a small wrist bone (trapeziectomy) versus removal plus ligament reconstruction (the Weilby procedure). Sixty patients were randomly assigned to one surgery. The goal was to see which provides better pain relief and hand function. Results will help guide treatment choices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surgical procedure
What this could lead to: If this trial succeeds, it could help doctors choose the best surgical option for thumb arthritis, potentially improving pain and function with fewer complications.
What could go wrong: This is a small, completed trial with only 60 participants. Results may not apply to everyone, and surgery always carries risks like infection or nerve damage.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, hand

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

THUMB OSTEOARTHRITIS

Contacts and locations

Locations

Dept. of Orthopedic Surgery and Traumatology, Kolding Hospital, Denmark

Kolding, 6000, Denmark
Division of Hand Surgery, Dept. of Orthopedics and Traumatology, Hospital of Southern Denmark

Sønderborg, 6400, Denmark

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